Bus transfers will operate between Heuston and Athlone on the Heuston to Galway and Heuston to Westport / Ballina routes this Bank Holiday weekend.
It's as track renewal, platform and essential maintenance works are being carried out across the rail network.
The €70m Ceannt Station redevelopment is continuing, which include a new roof, extra platforms and a new entrance.
Iarnród Eireann is advising the public to check timetables on its website before travelling between Saturday and Monday.
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Irish Rail's spokesperson Jane Cregan, says Galway ,Cork and Kerry routes will be interrupted during the works.
