Researchers at the University of Galway have gained a greater insight into the role inflammation plays in the progression of Huntington's disease.
The inherited disease causes the progressive death of nerve cells in the brain, having a broad impact on a person's functional abilities.
The study - published in the journal Communications Medicine - on the part of the brain that plays a role in emotion processing, decision-making and cognitive control.
It then looked at how that correlates with the degree of cell death and type and severity of symptoms, particularly mood-related symptoms in Huntington’s disease.
University of Galway Professor Andrea Kwakowsky from the School of Pharmacy and Medical Sciences is lead author of the study.
She says the findings on inflammation will help with approaches to treatments